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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Mucosal Immunol. 2010 Sep 15;4(1):102–111. doi: 10.1038/mi.2010.57

Figure 7. Flagellin administration induces adverse effects in TLR5-deficient mice.

Figure 7

Six to eight week old wild-type (WT) or TLR5-deficient (T5KO) mice were administered either 100 μL of PBS or flagellin (FliC; 25μg/mouse) in 100 μL PBS on alternate days over a period of 20 days. (A) At the end of the experiment, relative change in body weight between the 1st and the 10th injection was calculated. (B) Colonic MPO and (C) cecum MPO. (D) H&E stained colon from mice which received FliC. The results are representative of two independent experiments (n=8). * p<0.05