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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: J Hypertens. 2011 Feb;29(2):251–256. doi: 10.1097/HJH.0b013e3283407ffd

Table 2.

Hand vein responses to phenylephrine and dexmedetomidine

Phenylephrine Dexmedetomidine P-value
ED50 (ng/min) 177.8 ng/min (40.7– 436.5) 1.3 ng/min (0.45–5.37) <0.001*
Emax (%) 90.8 (82.2–99.6) 80.0 (64.7–95.2) <0.001

Data are expressed as median (IQR)

Emax – Maximal venoconstriction, expressed as the percentage reduction in vein diameter from maximal dilation

ED50 - The dose of phenylephrine and dexmedetomidine that produced 50% of maximum venoconstriction (Emax) for each subject

*

P-value for the comparison of ED50 of phenylephrine and dexmedetomidine in fmole/min (see also Figure 1)