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. 2010 Nov 1;286(1):290–298. doi: 10.1074/jbc.M110.163477

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© 2011 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 1. — A, membrane currents related to spontaneous and caffeine-induced Ca²⁺ release. Aa, representative recording of Na⁺-Ca²⁺ exchange currents and LCC activity in a rat atrial myocyte (2 days in vitro) caused by spontaneous and caffeine-induced Ca²⁺ release, Ab and Ac represent expanded sections from A. C, O₁, and O₂ indicate closed state and two open levels. B, representative recording from a myocyte cultured for 5 days. C, current/voltage relation of LCC unitary current (mean values from 11 different cells). D, nP_o of caffeine-induced LCC activity and density of whole cell NCX current calculated for myocytes of 2 and 5 days in culture. nP_o periods of 10 s in duration, starting at the peak of NCX current, were used.