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Increase of LCC activity through activation of purinergic receptors by 10 μm 2Mes-ATP. A, recording of spontaneous LCC activity in atrial myocyte (2 days in culture) without caffeine. Application of the P2X and P2Y1 agonist 2Mes-ATP reversibly increased LCC openings. Channel activity increased after a short delay of about 30 s and slowly decreased after removal of the agonist within 60 s. B, summarized nPo (n = 7).
