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Mechanosensitivity of LCC. A, representative current recording from a native myocyte (2 days in culture). Spontaneous LCC activity in isotonic bath solution (300 mosmol/kg) followed by hypotonic solution, which had the same ionic composition except that mannitol was omitted (270 mosmol/kg). B, nPo of LCC in native cells (n = 6) and Ad-Panx1-infected cells (day 5 in culture, n = 6).
