Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Selectivity of human HP1 homologs is driven by polar fingers. Surface representations are shown of the polar fingers for Cbx3 (left) and Cbx5 chromodomains (right) in complex with H3K9me3 peptide. Thr-6 and Arg-8 residues of the peptide are shown in the binding cleft. The β and γ methylene groups of conserved polar fingers are sandwiched by side chains of Thr-6 and Arg-8. The right panel is rotated by 90° with respect to the left panel.
