TABLE 2.
Enriched biological process terms for ligand-responsive genes
Enriched GO biological process terms for ligand-responsive genes are shown. “up” and “down” represent expression patterns. GO terms with small p values (p < 0.05) are highlighted in bold type.
| Biological process term | Up-regulated |
Down-regulated |
||||||
|---|---|---|---|---|---|---|---|---|
| E2 |
HRG |
E2 |
HRG |
|||||
| WT | TamR | WT | TamR | WT | TamR | WT | TamR | |
| Anatomical structure morphogenesis | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 0.0006 |
| Behavior | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 0.0037 | 1.0000 |
| Biosynthetic process | 0.2809 | 0.0013 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 0.2682 | 1.0000 |
| Catabolic process | 1.0000 | 0.0024 | 1.0000 | 0.3881 | 1.0000 | 1.0000 | 1.0000 | 1.0000 |
| Cell communication | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 0.0000 |
| Cell cycle | 0.0000 | 0.0000 | 1.0000 | 0.0034 | 1.0000 | 1.0000 | 1.0000 | 1.0000 |
| Cell proliferation | 0.0316 | 0.0020 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 |
| Cellular amino acid and derivative metabolic process | 1.0000 | 1.0000 | 0.0001 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 |
| Cellular component organization | 0.0001 | 0.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 0.5402 | 1.0000 |
| Cytoskeleton organization | 0.0415 | 0.0028 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 0.4604 | 1.0000 |
| Embryonic development | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 0.0009 |
| Metabolic process | 0.0107 | 0.0000 | 1.0000 | 0.1823 | 1.0000 | 1.0000 | 0.4082 | 1.0000 |
| Multicellular organismal development | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 0.0000 |
| Nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.2115 | 0.0000 | 1.0000 | 0.1506 | 1.0000 | 1.0000 | 1.0000 | 1.0000 |
| Organelle organization | 0.0000 | 0.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 0.2484 | 1.0000 |
| Primary metabolic process | 0.0041 | 0.0000 | 1.0000 | 0.0656 | 1.0000 | 1.0000 | 1.0000 | 1.0000 |
| Protein transport | 0.0062 | 1.0000 | 0.0164 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 |
| Regulation of biological process | 0.1097 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 0.0000 |
| Response to abiotic stimulus | 1.0000 | 0.0142 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 |
| Response to external stimulus | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 0.0290 |
| Response to stress | 0.3350 | 0.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 0.2041 | 1.0000 |
| Signal transduction | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 0.0000 |
| Symbiosis, encompassing mutualism through parasitism | 1.0000 | 0.8250 | 0.3863 | 1.0000 | 0.0268 | |||
| Translation | 1.0000 | 1.0000 | 0.0275 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | |
| Transport | 0.0661 | 1.0000 | 0.0406 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 |