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. 2010 Dec 30;5(12):e15224. doi: 10.1371/journal.pone.0015224

Figure 5. qPCR results for five miRNAs clustered on Xq27.3 and their putative target genes in ∼50 ccRCC patients.

Figure 5

The expression of five miRNAs clustered on Xq27.3, as well as the expression of some of their most interesting predicted targets was evaluated in a large sample panel. The height of the columns in the chart represents the log-transformed average fold change (tumor/normal) in expression across all patients for each of the genes validated; bars represent the standard errors. The number of samples (n) used in the validation assay is shown beside each standard error bar. Generally, miRNAs were downregulated in 76.7% to 88.6% of the patients, while the target genes were upregulated in 63.8% to 84.9% of the patients.