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. 2010 Dec 31;5(12):e14338. doi: 10.1371/journal.pone.0014338

Figure 4. EGCI vs. GCI in simulated data.

Figure 4

A. Effect of known genetic and environmental factors versus known genetic factors alone for Crohn's Disease. The AUCs of the two curves are 0.74 and 0.78. We considered smoking as the environmental variable in addition to the genetic factors. B. Effect of known genetic and environmental factors versus known genetic factors alone for Type 2 Diabetes. The AUCs of the two curves are 0.58 and 0.79 respectively. We considered Body Mass Index, alcohol intake and smoking frequency as the environmental factors for Type 2 Diabetes, in addition to the genetic factors. C. Effect of genetic and environmental factors versus genetic factors alone for Rheumatoid Arthritis. The AUCs of the two curves are 0.685 and 0.690. We considered smoking as the environmental variable in addition to the genetic factors. The relative risks for the environmental variables are provided in Table 4.