Table 1. Allele frequencies and the relative risks of Type 2 Diabetes, Crohn's Disease and Rheumatoid Arthritis SNPs.
Disease | dbSNP rs id | Relative risk1 for RR | Relative Risk1 for RN | Frequency2 of RR | Frequency2 of RN |
Type 2 Diabetes | rs10012946 [6] | 1.1464 | 1.0239 | 0.5000 | 0.4667 |
rs10811661 [7] | 1.3008 | 1.1282 | 0.6667 | 0.2500 | |
rs1801282 [7] | 1.4128 | 1.2417 | 0.8667 | 0.1167 | |
rs4402960 [7] | 1.1602 | 1.1233 | 0.1167 | 0.3500 | |
rs4506565 [5] | 1.6133 | 1.2738 | 0.0847 | 0.3729 | |
rs5215 [7] | 1.1681 | 1.0935 | 0.1000 | 0.6167 | |
rs8050136 [8] | 1.3609 | 1.1176 | 0.1167 | 0.6667 | |
rs9494266 [9] | 1.4909 | 1.2296 | 0.0169 | 0.0847 | |
rs10923931 | 1.1948 | 1.0947 | 0.0167 | 0.2000 | |
rs4607103 | 1.1392 | 1.0681 | 0.6333 | 0.3500 | |
rs7961581 | 1.1355 | 1.0664 | 0.0500 | 0.3667 | |
rs864745 | 1.1530 | 1.0747 | 0.3158 | 0.4035 | |
rs5015480 | 1.1456 | 1.0451 | 0.3167 | 0.4833 | |
Crohn's Disease | rs10883365 | 1.6154 | 1.1989 | 0.3000 | 0.4000 |
rs2066845 | 11.4381 | 3.0164 | 0.0000 | 0.0333 | |
rs10489276 | 1.4130 | 1.1888 | 0.0333 | 0.3667 | |
rs1894603 | 1.4608 | 1.2088 | 0.2542 | 0.4407 | |
rs4871611 | 1.1654 | 1.0795 | 0.3667 | 0.5000 | |
rs6679677 | 1.7116 | 1.3085 | 0.7167 | 0.2833 | |
rs17234657 | 2.3052 | 1.5360 | 0.0667 | 0.2000 | |
rs11175593 | 2.3532 | 1.5353 | 0.0000 | 0.0333 | |
rs11584383 | 1.3899 | 1.1790 | 0.4333 | 0.4500 | |
rs1456893 | 1.4371 | 1.1989 | 0.3667 | 0.5333 | |
rs1736135 | 1.3898 | 1.1790 | 0.3000 | 0.5000 | |
rs17582416 | 1.3432 | 1.1590 | 0.1667 | 0.4333 | |
rs2872507 | 1.2527 | 1.1193 | 0.2167 | 0.5000 | |
rs3764147 | 1.5580 | 1.2484 | 0.0847 | 0.3220 | |
rs4263839 | 1.4852 | 1.2188 | 0.4167 | 0.4667 | |
rs744166 | 1.3898 | 1.1790 | 0.3276 | 0.4483 | |
rs762421 | 1.2751 | 1.1292 | 0.2500 | 0.4833 | |
rs10210302 | 1.8433 | 1.1890 | 0.3000 | 0.5000 | |
rs7746082 | 1.3663 | 1.1690 | 0.1017 | 0.4915 | |
rs7927894 | 1.3432 | 1.1591 | 0.2333 | 0.3833 | |
rs9858542 | 1.8316 | 1.0895 | 0.0333 | 0.4167 | |
rs11805303 | 1.8525 | 1.3875 | 0.1000 | 0.3833 | |
rs1000113 | 1.9102 | 1.5354 | 0.0000 | 0.0667 | |
rs2066844 | 3.2543 | 1.9609 | 0.0000 | 0.2203 | |
rs17221417 | 1.9118 | 1.2883 | 0.1000 | 0.5167 | |
rs2542151 | 1.9997 | 1.2980 | 0.0500 | 0.2833 | |
rs10761659 | 1.5461 | 1.2287 | 0.2333 | 0.6333 | |
Rheumatoid | rs10118357 [10] | 1.7278 | 1.3152 | 0.2712 | 0.5254 |
Arthritis | rs13207033 [10] | 1.7559 | 1.3258 | 0.6667 | 0.3167 |
rs6457617 [5] | 5.0847 | 2.3414 | 0.2167 | 0.5667 | |
rs6679677 [11] | 3.1672 | 1.6847 | 0.0000 | 0.2833 | |
rs6920220 [5] | 1.7023 | 1.1965 | 0.0000 | 0.3500 |
1. The relative risks provided here were calculated using the GCI methodology, as explained in the Methods section. RR means risk-risk genotype and RN means risk-nonrisk genotype.
2. The allele frequencies are taken from the HapMap project's CEU population.