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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Inflamm Bowel Dis. 2010 Sep 27;17(5):1149–1162. doi: 10.1002/ibd.21463

Figure 8. AhR activation in patients with IBD.

Figure 8

(A) CYP1A1 mRNA gene expression level is increased in IBD patients compared with control. (B) IL8 mRNA gene expression increases during the inflammatory process in IBD patients. Control n=15, IBD n=25. Data are expressed as median. (C, D) Fluorescent Immunohistochemistry staining of the AhR in a control patient (C) versus a patient with Crohn’s disease (D). Representative images are shown of biopsies obtained from a control subject (C) and from a patient with Crohn’s disease (D). Red staining indicates binding of the antibody to human AhR. All samples were counterstained with DAPI (blue) to visualize nuclei. Magnification is 20X. E - Enterocytes and LP- Lamina Propria.