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Overepression of PSD-95 in Immature Neurons Reduces Glycine-Independent Desensitization. A. Representative traces of NMDAR responses in immature neurons overexpressing GFP, PSD-95 PDZ1-2-GFP or PSD-95-GFP. B. Overexpression of PSD-95 PDZ1-2-GFP or PSD-95-GFP in immature hippocampal neurons results in decreased desensitization compared to GFP-transfected controls. GFP n=7; PSD-95 PDZ1-2-GFP, n=6; PSD-95-GFP, n=12; *P<0.05, **P<0.01 by one-way ANOVA followed by Bonferroni post-test.
