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. 2010 Oct 12;10(1):M110.004036. doi: 10.1074/mcp.M110.004036

Table I. A list of proteins increased in abundance in mpkCCD cells in response to long-term (5 days) 0.1 nM dDAVP exposure. Results were calculated from all peptides quantified using SILAC in three LTQ-FT-ICR data-dependent experiments. Shown are log2 values of the mean of all peptide ratios (dDAVP: vehicle or D/V). All passed two-tailed t-test against log2(1) (p < 0.05).

Protein name Gene symbol RefSeq no. No. of peptides Log2(D/V) (Mean ± S.E.)
aquaporin 2 Aqp2 NP_033829 3 4.5 ± 0.6
MON2 homolog Mon2 NP_700444 5 2.8 ± 0.4
hexose-6-phosphate dehydrogenase H6pd NP_775547 9 2.1 ± 0.2
A kinase (PRKA) anchor protein (gravin) 12 Akap12 NP_112462 24 2.0 ± 0.1
carnitine palmitoyltransferase 1A liver Cpt1a NP_038523 23 2.0 ± 0.1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1 Uap1l1 NP_001028465 8 1.9 ± 0.2
spectrin beta 3 Spnb3 NP_067262 53 1.4 ± 0.1
gasdermin C2 Gsdmc2 NP_808580 4 1.3 ± 0.4
isocitrate dehydrogenase 1 (NADP+), soluble Idh1 NP_034627 20 1.3 ± 0.1
microtubule-actin crosslinking factor 1 Macf1 NP_033730 11 1.3 ± 0.1
glutathione S-transferase, theta 3 Gstt3 NP_598755 7 1.2 ± 0.3
glutathione S-transferase, theta 2 Gstt2 NP_034491 3 1.1 ± 0.2
MAL2 proteolipid protein Mal2 NP_849251 1 1.1 ± 0.2
glutathione S-transferase, alpha 4 Gsta4 NP_034487 10 1.0 ± 0.1
dystonin isoform b Dst NP_604443 2 0.9 ± 0.3
cathepsin D Ctsd NP_034113 8 0.9 ± 0.2
aldo-keto reductase family 1, member C19 Akr1c19 NP_001013807 7 0.9 ± 0.1
indolethylamine N-methyltransferase Inmt NP_033375 7 0.8 ± 0.2
solute carrier family 25, member 13 Slc25a13 NP_056644 25 0.8 ± 0.1
legumain Lgmn NP_035305 4 0.8 ± 0.1
carbonic anhydrase II Car2 NP_033931 9 0.7 ± 0.2
GDP-mannose 4,6-dehydratase Gmds NP_666153 5 0.7 ± 0.2
glutathione S-transferase, pi 1 Gstp1 NP_038569 13 0.7 ± 0.2
LIM domain and actin binding 1 isoform b Lima1 NP_075550 2 0.7 ± 0.1
glutathione S-transferase mu 1 Gstm1 NP_034488 17 0.7 ± 0.1
abhydrolase domain containing 14b Abhd14b NP_083907 8 0.6 ± 0.2
ATP citrate lyase Acly NP_598798 25 0.6 ± 0.1
spectrin alpha 2 Spna2 NP_001070022 124 0.6 ± 0.1
caldesmon 1 Cald1 NP_663550 6 0.6 ± 0.1
ciliary rootlet coiled-coil isoform 1 Crocc NP_742120 1 0.6 ± 0.1
transglutaminase 2, C polypeptide Tgm2 NP_033399 7 0.6 ± 0.1
ubiquilin 2 Ubqln2 NP_061268 2 0.6 ± 0.1
F-box protein 18 Fbxo18 NP_056607 1 0.5 ± 0.2
SMC hinge domain containing 1 Smchd1 NP_083163 6 0.5 ± 0.2
RalGDS-like protein 3 Rgl3 NP_076111 9 0.5 ± 0.2
hydroxyacyl-Coenzyme A dehydrogenase type II Hsd17b10 NP_058043 12 0.5 ± 0.2
NADH dehydrogenase (ubiquinone) Fe-S protein 1 Ndufs1 NP_663493 7 0.5 ± 0.1
flightless I homolog Flii NP_071292 12 0.5 ± 0.1
calpastatin Cast NP_033947 4 0.5 ± 0.1
radixin isoform a Rdx NP_033067 18 0.5 ± 0.1
moesin Msn NP_034963 21 0.5 ± 0.1
cytochrome b5 type B precursor Cyb5b NP_079834 5 0.5 ± 0.1
solute carrier family 25, member 12 Slc25a12 NP_766024 10 0.5 ± 0.1
glutamate dehydrogenase 1 Glud1 NP_032159 9 0.5 ± 0.1
alanyl-tRNA synthetase Aars NP_666329 22 0.5 ± 0.1
brain abundant, membrane attached signal protein 1 Basp1 NP_081671 8 0.5 ± 0.1
osteoclast stimulating factor 1 Ostf1 NP_059071 3 0.4 ± 0.2
fatty acid synthase Fasn NP_032014 71 0.4 ± 0.2
tight junction protein 2 Tjp2 NP_035727 18 0.4 ± 0.2
N-acylsphingosine amidohydrolase 1 Asah1 NP_062708 10 0.4 ± 0.1
cytochrome P450 reductase Por NP_032924 23 0.4 ± 0.1
actinin, alpha 1 Actn1 NP_598917 49 0.4 ± 0.1
keratin complex 2, basic, gene 17 Krt2 NP_034798 9 0.4 ± 0.1
transmembrane protein 33 isoform 2 Tmem33 NP_084384 3 0.4 ± 0.1
peroxiredoxin 5 precursor Prdx5 NP_036151 12 0.4 ± 0.1
actinin alpha 4 Actn4 NP_068695 37 0.4 ± 0.1
keratin 18 Krt18 NP_034794 29 0.4 ± 0.1
p21-activated kinase 3 Pak3 NP_032804 6 0.4 ± 0.1
keratin 6A Krt6a NP_032502 13 0.4 ± 0.1
delta-aminolevulinic acid dehydratase Alad NP_032551 11 0.4 ± 0.1
plastin 3 precursor Pls3 NP_663604 12 0.4 ± 0.1
CNDP dipeptidase 2 Cndp2 NP_075638 13 0.4 ± 0.1
pyruvate carboxylase Pcx NP_032823 12 0.4 ± 0.1
nicotinamide phosphoribosyltransferase Nampt NP_067499 14 0.4 ± 0.1
clathrin, heavy polypeptide (Hc) Cltc NP_001003908 76 0.3 ± 0.1
pyruvate dehydrogenase (lipoamide) beta Pdhb NP_077183 5 0.3 ± 0.1
electron transferring flavoprotein, alpha polypeptide Etfa NP_663590 13 0.3 ± 0.1
family with sequence similarity 129, member A Fam129a NP_071301 20 0.3 ± 0.1
superoxide dismutase 2, mitochondrial Sod2 NP_038699 4 0.3 ± 0.1
keratin 6L Krt79 NP_666175 9 0.3 ± 0.1
spectrin beta 2 isoform 1 Spnb2 NP_787030 62 0.3 ± 0.1
tight junction protein 1 Tjp1 NP_033412 10 0.3 ± 0.1
keratin 5 Krt5 NP_081287 17 0.3 ± 0.1
phosphogluconate dehydrogenase Pgd NP_001074743 10 0.3 ± 0.1
N-myc downstream regulated 1 Ndrg1 NP_032707 9 0.3 ± 0.1
p21-activated kinase 2 Pak2 NP_796300 14 0.3 ± 0.1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2 isoform 3 Smarcc2 NP_937803 10 0.3 ± 0.1
seryl-tRNA synthetase Sars NP_035449 15 0.3 ± 0.1
oxidation resistance 1 isoform A Oxr1 NP_570955 11 0.3 ± 0.1
keratin complex 2, basic, gene 8 Krt8 NP_112447 40 0.3 ± 0.1
Wiskott-Aldrich syndrome-like Wasl NP_082735 5 0.3 ± 0.1
SKI interacting protein Snw1 NP_079783 3 0.2 ± 0.1
drebrin-like isoform 2 Dbnl NP_038838 4 0.2 ± 0.1
neural precursor cell expressed, developmentally down-regulated gene 4 Nedd4 NP_035020 17 0.2 ± 0.1
heat shock protein 9 Hspa9 NP_034611 29 0.2 ± 0.1
periplakin Ppl NP_032935 74 0.2 ± 0.1
isoleucine tRNA synthetase Iars NP_742012 22 0.2 ± 0.1
chaperonin containing Tcp1, subunit 5 (epsilon) Cct5 NP_031663 15 0.2 ± 0.1
dipeptidyl peptidase III Dpp3 NP_598564 14 0.2 ± 0.1
valosin containing protein Vcp NP_033529 24 0.2 ± 0.1
phospholipase C beta 3 Plcb3 NP_032900 23 0.2 ± 0.1
aconitase 2, mitochondrial Aco2 NP_542364 35 0.2 ± 0.1
chaperonin subunit 2 (beta) Cct2 NP_031662 13 0.2 ± 0.1
coatomer protein complex, subunit gamma isoform 1 Copg NP_059505 8 0.2 ± 0.1
ubiquitin-activating enzyme E1 isoform 1 Uba1 NP_033483 14 0.2 ± 0.1
ubiquinol cytochrome c reductase core protein 2 Uqcrc2 NP_080175 7 0.1 ± 0.1
B-cell receptor-associated protein 37 Phb2 NP_031557 12 0.1 ± 0.1
heat shock protein 4 Hspa4 NP_032326 30 0.1 ± 0.1
keratin 19 Krt19 NP_032497 30 0.1 ± 0.1
peroxiredoxin 4 Prdx4 NP_058044 3 0.1 ± 0.1
voltage-dependent anion channel 2 Vdac2 NP_035825 10 0.1 ± 0.1
high density lipoprotein binding protein Hdlbp NP_598569 26 0.1 ± 0.1