Table 2.
Comparison of control women and women with spontaneous 46,XX primary ovarian insufficiency (POI) with regard to frequency of mild, moderate, and severe depressive states as assessed by the Center for Epidemiologic Studies Depression Scale (CES-D) and high anxiety state as assessed by the State-Trait Anxiety Inventory.
| POI (N=98) N (%) | Controls (N=60) N (%) | P | |
|---|---|---|---|
| Depression1 | <0.0022 | ||
| None (CES-D< 16) | 57 (58.8) | 49 (81.7) | |
| Mild (CES-D 16 -20) | 14 (14.4) | 6 (10.0) | |
| Moderate (CES-D 21–26) | 8 (8.3) | 2 (3.3) | |
| Severe (CES-D ≥ 27) | 18 (18.6) | 3 (5.0) | |
| High Anxiety3 (> 44) | 37 (37.8) | 5 (8.3) | < 0.0014 |
1
Scores may range from 0 to 60, with higher scores reflecting greater depression.
2
Kruskal-Wallis test for singly ordered contingency tables.
3
Scores may range from 20 to 80, with higher scores reflecting greater anxiety.
4
Fisher’s exact test.