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Riboswitch inactivation of ribosomal docking and initiation of translation. A) A RNA aptamer in a three dimensional conformation open for ribosomal docking in 5′UTR. B) A RNA aptamer binds to ligand, which causes a conformational change, formation of a hairpin turn, and sequestration of the ribosomal docking site upstream of the AUG start codon. This inhibits the initiation of protein translation.
