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. Author manuscript; available in PMC: 2011 Jan 3.
Published in final edited form as: J Drug Deliv Sci Technol. 2010 May;20(3):163–169. doi: 10.1016/s1773-2247(10)50025-x

Figure 4.

Figure 4

Translational control of gene expression via the RISC complex on siRNA. A) A double stranded RNA complex is added. The RISC complex binds to the anti-sense strand (AS) via the Argonaut protein. B) Complementary mRNA binds the anti-sense strand. C) Complementary mRNA is cleaved by RISC, which down regulates the translation of target mRNA.