Table 2.
Patient characteristics (COHORT1) by study site
| Study Site | Patient | Birth Year | Age at Last Scr (years) | eGFR (ml/min) | % with ESRD | Age at ESRD (years) | Time to ESRD (years) | C1 | C2 | C3 | C4 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Toronto, Canada | 174 | 1952 ± 13 | 43.3 ± 11.4 | 51.7 ± 44.1 | 41.4 | 49.8 ± 8.3 | 43.3 ± 11.4 | 0.0050 ± 0.0200 | 0.0006 ± 0.0200 | −0.0100 ± 0.0300 | 0.0020 ± 0.0200 |
| Newfoundland, Canada | 79 | 1957 ± 12 | 41.5 ± 11.5 | 70.7 ± 42.3 | 19.0 | 47.9 ± 8.8 | 41.5 ± 11.5 | 0.0200 ± 0.0100 | −0.0040 ± 0.0400 | 0.0040 ± 0.0300 | −0.0030 ± 0.0300 |
| Denver, CO | 216 | 1955 ± 16 | 40.0 ± 15.0 | 64.9 ± 45.0 | 31.5 | 51.4 ± 11.3 | 40.0 ± 15.0 | −0.0020 ± 0.0200 | 0.0030 ± 0.0200 | −0.0020 ± 0.0200 | −0.0030 ± 0.0200 |
| Brussels, Belgium | 21 | 1946 ± 19 | 46.7 ± 10.3 | 23.6 ± 35.5 | 71.4 | 48.6 ± 10.4 | 46.7 ± 10.3 | −0.0080 ± 0.0300 | 0.0060 ± 0.0100 | 0.0040 ± 0.0200 | −0.0030 ± 0.0300 |
| Sofia, Bulgaria | 22 | 1949 ± 13 | 45.6 ± 11.9 | 45.8 ± 31.1 | 40.0 | 54.4 ± 5.1 | 45.6 ± 11.9 | −0.0300 ± 0.0200 | 0.0100 ± 0.0200 | 0.0100 ± 0.0200 | −0.0060 ± 0.0200 |
| Leiden, Netherlands | 41 | 1945 ± 9.5 | 49.5 ± 8.7 | 27.6 ± 28.8 | 68.3 | 52.5 ± 6.5 | 49.5 ± 8.7 | 0.0060 ± 0.0200 | 0.0006 ± 0.0200 | −0.0100 ± 0.0100 | 0.0100 ± 0.0200 |
| Aachen, Germany | 12 | 1962 ± 14 | 39.3 ± 10.7 | 69.4 ± 48.6 | 33.3 | 50.5 ± 8.7 | 39.3 ± 10.7 | −0.0020 ± 0.0200 | 0.0010 ± 0.0100 | −0.0060 ± 0.0100 | 0.0050 ± 0.0200 |
| Modena, Italy | 28 | 1956 ± 13 | 43.8 ± 11.4 | 54.4 ± 44.0 | 28.6 | 49.4 ± 10.8 | 43.8 ± 11.4 | −0.0300 ± 0.0080 | −0.0050 ± 0.0200 | −0.0060 ± 0.0100 | −0.0090 ± 0.0200 |
| Barcelona, Spain | 21 | 1948 ± 9 | 46.0 ± 5.6 | 27.0 ± 35.0 | 76.2 | 46.6 ± 6.1 | 46.0 ± 5.6 | −0.0300 ± 0.0200 | −0.0020 ± 0.0200 | −0.0100 ± 0.0200 | 0.0080 ± 0.0100 |
| Oviedo, Spain | 22 | 1948 ± 8 | 54.4 ± 6.8 | 19.1 ± 20.4 | 82.0 | 53.7 ± 6.6 | 54.4 ± 6.8 | −0.0300 ± 0.0200 | −0.0090 ± 0.0100 | −0.0070 ± 0.0100 | 0.0060 ± 0.0200 |
| Kuopio, Finland | 119 | 1952 ± 16 | 44.5 ± 15.3 | 66.1 ± 37.4 | 21.0 | 54.3 ± 13.1 | 44.5 ± 15.3 | 0.0400 ± 0.0200 | 0.0200 ± 0.0200 | 0.0200 ± 0.0200 | 0.0010 ± 0.0200 |
| Nicosia, Cyprus | 20 | 1962 ± 14 | 40.6 ± 12.8 | 55.9 ± 44.0 | 40.0 | 50.4 ± 5.6 | 40.6 ± 12.8 | −0.0700 ± 0.0100 | 0.0020 ± 0.0100 | 0.000007 ± 0.0200 | −0.0100 ± 0.0200 |
| Athens, Greece | 19 | 1947 ± 9 | 50.5 ± 10.2 | 10.0 | 100.0 | 50.5 ± 10.2 | 50.5 ± 10.2 | −0.0400 ± 0.0200 | −0.0060 ± 0.0100 | 0.0040 ± 0.0100 | −0.0030 ± 0.0100 |
| All centers | 794 | 1953 ± 15 | 43.3 ± 13.2 | 55.1 ± 43.5 | 38.3 | 50.8 ± 9.5 | 43.3 ± 13.2 | 0.0020 ± 0.0300 | −0.0002 ± 0.0300 | −0.0010 ± 0.0200 | −0.0005 ± 0.0200 |
All continuous variables are mean ± SD. Scr, serum creatinine.