Table 5.
Trough concentrations of belatacept
4-Week Schedule |
8-Week Schedule |
||||
---|---|---|---|---|---|
Months after Transplantation | n | Trough Concentration (μg/ml) Geometric Mean (CV%) | Months after Transplantation | n | Trough Concentration (μg/ml) Geometric Mean (CV%) |
13 | 49 | 3.43 (55) | 13 | 24 | 0.13 (128) |
24 | 46 | 3.95 (52) | 25 | 38 | 0.14 (97) |
36 | 39 | 4.76 (43) | 37 | 30 | 0.19 (193) |
48 | 24 | 4.43 (52) | 49 | 20 | 0.21 (150) |
60 | 15 | 4.85 (36) | 59 | 15 | 0.17 (93) |
Patients received a 5-mg/kg infusion 4 or 8 weeks before sample collection. n = number of individual patient samples available for analysis at database lock.