Table 1.

Computational analysis identified miR-192 and miR-215 as good candidates to target WNK1 3′UTR

Methods	hsa-miR-192	hsa-miR-215
Cross-species comparison
TargetScan 5.1	+	+
Miranda	+	+
DianamicroT 3.0	−	+
miRTarget2	+	+
Pattern-based (RNA 22)	−	+
SVM classifier-based (miTarget)	−	+
Central loop integrating	+	+
miRNA:target interaction filter	True	False

Cross-species comparison, pattern-based, SVM classifier–based, or central loop integrating tools were used to predict the presence (+) or absence (−) of miR-192 or miR-215 binding sites in WNK1 3′UTR. Postfitting of the predictions was done according to Yang et al.²⁵