TABLE 1.
EFFECT OF FREEZE DRYING ON DRUG CONTENT AND PARTICLE SIZE
| Batch code | Composition |
Drug content (µg/mM of lipid) |
Mean particle size (µm) |
||||
|---|---|---|---|---|---|---|---|
| CH | PL 90 G | PL 90 H | Before freeze drying | After freeze drying | Before freeze drying | After freeze drying | |
| BL-1 | 2 | 1 | 9 | 6037.18±289.30 | 6097.66±174.28 | 4.98 | 6.12 |
| BL-4 | 2 | 3 | 7 | 5324.24±66.07 | 5238.64±210.20 | 4.20 | 6.17 |
| BL-7 | 2 | 5 | 5 | 4669.64±157.18 | 4813.59±89.48 | 3.97 | 6.28 |
| BL-10 | 6 | 1 | 9 | 2842.53±262.39 | 2950.89±195.07 | 6.47 | 7.29 |
| BL-13 | 6 | 3 | 7 | 2580.20±114.12 | 2786.99±87.54 | 4.50 | 7.18 |
| BL-16 | 6 | 5 | 5 | 2590.80±223.51 | 2820.34±118.20 | 5.47 | 6.74 |
| BL-19 | 10 | 1 | 9 | 2200.42±149.00 | 2398.61±169.05 | 6.47 | 7.85 |
| BL-22 | 10 | 3 | 7 | 2525.54±139.05 | 2699.29±153.29 | 6.27 | 7.49 |
| BL-25 | 10 | 5 | 5 | 2440.53±80.84 | 2614.17±121.55 | 6.58 | 7.95 |