Figure 3 Contrast of affected limb movements postintervention vs preintervention for the dual group

Contrasting postintervention vs preintervention movements of the affected upper limb overlaid onto a standard anatomic template (p < 0.05, familywise error corrected; cluster extent threshold: 20 voxels). Both wrist (blue) and elbow (red) movements yielded stronger activations of ipsilesional primary motor/premotor cortex after the 5-day intervention. For the elbow movement task, the cluster was located in primary motor cortex (Talairach coordinates: x = −18, y = −23, z = 68; T = 5.39). For the wrist movement task, one cluster was located at the border between primary motor and premotor cortex (x = −40, y = −8, z = 60; T = 5.28); an additional positive activation change was found in the contralesional inferior frontal gyrus (x = 56, y = 29, z = 14; T = 5.66).