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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Osteoarthritis Cartilage. 2010 Sep 9;18(11):1509–1517. doi: 10.1016/j.joca.2010.08.014

Figure 4.

Figure 4

p38 and ERK MAP Kinase Activation at 12 and 24 hr Post-impact. Western blot results are shown for cartilage from non-impacted control explants (“C”), or from impact sites (“I”) and annulus sites (“A”) from injured explants. (A) Representative blots of extracts from cartilage harvested at 12 or 24 hours after impact. The blots were probed for total p38 or phosphorylated p38. (B) Fold increase in phosphorylation (impact or annulus versus control) based on densitometric analysis of western blots from at least 3 individual experiments. Error bars stand for 95% confidence intervals. (C) Western blots were probed for total and phosphorylated ERKs at 24 hrs in untreated control or impacted cartilage from five individual osteo-chondral explants. Results are shown for control, impact and annulus sits (“C”, “I”, “A”). (D) Average fold increase in phosphorylation (relative to non-impacted control) based on densitometric analysis from six individual experiments. Error bars show 95% confidence intervals.