Table 1.

Pairwise overlaps between human interaction databases in terms of shared functional interactions as of September 2010

	Reactome	Kegg	Humancyc	Pid	Biocarta	Netpath	Inoh	Ehmn	Intact-ss	Intact-ls	Dip	Mint	Hprd	Spike	Biogrid	Pig	Corum	Mips-mppi
Reactome	5953	286	147	157	85	53	199	327	152	19	69	73	387	125	233	489	108	8
Kegg	286	1747	242	0	4	0	382	1135	0	0	0	0	0	0	0	0	0	0
Humancyc	147	242	1765	1	4	0	122	254	6	2	3	4	21	2	11	33	6	0
Pid	157	0	1	5664	346	257	94	0	129	12	109	106	427	257	351	520	95	15
Biocarta	85	4	4	346	2260	129	51	8	62	7	41	39	110	173	114	141	40	7
Netpath	53	0	0	257	129	2139	63	0	262	13	201	277	1304	475	694	1121	33	19
Inoh	199	382	122	94	51	63	2346	395	30	5	29	28	75	54	71	98	23	1
Ehmn	327	1135	254	0	8	0	395	3873	0	0	0	0	0	4	0	0	0	0
Intact-ss	152	0	6	129	62	262	30	0	12 352	416	427	3757	3743	4681	2892	6303	201	65
Intact-ls	19	0	2	12	7	13	5	0	416	12 215	36	3798	5152	8592	6334	10 836	16	12
Dip	69	0	3	109	41	201	29	0	427	36	1701	378	842	522	736	1286	64	29
Mint	73	0	4	106	39	277	28	0	3757	3798	378	13 994	6766	5893	4928	11 834	99	50
Hprd	387	0	21	427	110	1304	75	0	3743	5152	842	6766	404 10	112 38	158 68	318 76	468	249
Spike	125	0	2	257	173	475	54	4	4681	8592	522	5893	112 38	222 32	9975	181 00	140	113
Biogrid	233	0	11	351	114	694	71	0	2892	6334	736	4928	158 68	9975	334 35	193 15	261	195
Pig	489	0	33	520	141	1121	98	0	6303	108 36	12 86	118 34	318 76	181 00	193 15	100 459	372	302
Corum	108	0	6	95	40	33	23	0	201	16	64	99	468	140	261	372	1667	9
Mips-mppi	8	0	0	15	7	19	1	0	65	12	29	50	249	113	195	302	9	323

The numbers in the main diagonal denote the distinct interactions imported from each database.