Table 1.
Summary of RNAP-II bound promoters identified in various tissues/cell types for human and mouse using ChIP-seq data sets
Species | Tissue/cell type | No. of known promoters | No. of novel promoters | No. of tissue/ cell-specific promoters | No. of CpG promoters | No. of bidirectional promoters | No. of total promoters |
---|---|---|---|---|---|---|---|
Mouse | Brain | 15 948 | 5270 | 3978 | 13 864 | 1373 | 21 218 |
Liver | 12 319 | 3189 | 1642 | 10 421 | 1250 | 15 508 | |
Kidney | 15 059 | 4632 | 1995 | 12 879 | 1348 | 19 691 | |
Spleen | 9089 | 2121 | 806 | 8273 | 1067 | 11 210 | |
Lung | 15 373 | 5142 | 1935 | 13 986 | 1374 | 20 515 | |
Embryonic stem cell(V6.5) | 11 895 | 2880 | 2745 | 12 063 | 1314 | 14 775 | |
Mouse embryonic fibroblasts B4 | 10 558 | 2261 | 273 | 10 898 | 1241 | 12 819 | |
Mouse embryonic fibroblasts B6 | 11 887 | 2761 | 706 | 10 886 | 1237 | 14 648 | |
Bone marrow-derived macrophages (untreated) | 13 320 | 3977 | 870 | 12 038 | 1298 | 17 297 | |
Bone marrow-derived macrophages (2 h) | 12 647 | 3713 | 566 | 11 846 | 1294 | 16 260 | |
Bone marrow-derived macrophages (4 h) | 13 119 | 4041 | 688 | 11 926 | 1292 | 17 160 | |
3T3-L1 cells (untreated) | 8489 | 1373 | 113 | 8597 | 1038 | 9862 | |
3T3-L1 cells (Day 1) | 8684 | 1626 | 154 | 8803 | 1072 | 9310 | |
3T3-L1 cells (Day 2) | 8508 | 1593 | 174 | 8415 | 1042 | 10 101 | |
3T3-L1 cells (Day 3) | 8374 | 1540 | 136 | 8371 | 1035 | 9914 | |
3T3-L1 cells (Day 4) | 6976 | 1422 | 194 | 6793 | 848 | 8398 | |
3T3-L1 cells (Day 6) | 4039 | 1443 | 927 | 4030 | 511 | 5482 | |
Total | 29 517 | 18 849 | 17 902 | 24 587 | 1801 | 48 366 | |
Human | Jurkat cells | 7417 | 1403 | 541 | 7653 | 792 | 8820 |
K562 cells | 16 410 | 8012 | 6422 | 16 918 | 1320 | 24 422 | |
Lymphoblastoid cells | 19 617 | 8998 | 6629 | 20 682 | 1311 | 28 615 | |
NB4 cells | 12 925 | 2944 | 916 | 13 650 | 1156 | 15 869 | |
HeLa_S3 cells | 13 982 | 3502 | 2101 | 14 812 | 1212 | 17 484 | |
CD4 + T cells | 14 329 | 4137 | 1336 | 15 740 | 1220 | 18 466 | |
CD4 + T cells (2 h) | 7354 | 1267 | 174 | 7955 | 882 | 8621 | |
CD4 + T cells (12 h) | 11 470 | 2389 | 377 | 12 740 | 1172 | 13 859 | |
Total | 24 967 | 17 926 | 18 496 | 27 488 | 1501 | 42 893 |