Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
HMGB1-mediated IRI involves TLR4 signaling. TLR4−/− mice treated with control Ab were protected against renal dysfunction (A) and tubular damage (B) with no further protection afforded by anti-HMGB1 Ab administration. The data shown are the means ± SD. n = 9 per group.
