Table 1.
Urinary and blood parameters from mice kept on a standard-salt diet
| Parameter | KO | Control |
|---|---|---|
| Body weight (g) | ||
| females | 21.30 ± 0.66 (n = 13) | 22.10 ± 0.65 (n = 24) |
| males | 27.70 ± 0.89 (n = 13) | 28.20 ± 1.08 (n = 15) |
| Food intake (g/g body wt per 24 h) | 0.13 ± 0.01 (n = 8) | 0.12 ± 0.01 (n = 10) |
| Na+ intake (mmol/24 h) | 0.27 ± 0.03 (n = 8) | 0.26 ± 0.03 (n = 10) |
| Urinary Na+ (mmol/24 h) | 0.23 ± 0.01 (n = 31)a | 0.19 ± 0.01 (n = 46) |
| Urinary Na+ (mM) | 136 ± 11 (n = 31) | 155 ± 7 (n = 46) |
| Urinary K+ (mmol/24 h) | 0.33 ± 0.04 (n = 31) | 0.28 ± 0.03 (n = 46) |
| Urinary K+ (mM) | 213 ± 38 (n = 31) | 242 ± 23 (n = 46) |
| Urinary osm (mosm/kgH2O) | 1809 ± 119 (n = 26)b | 2442 ± 133 (n = 39) |
| Urine output (ml/g body wt per 24 h) | 0.085 ± 0.008 (n = 31)b | 0.055 ± 0.004 (n = 46) |
| Water intake (ml/g body wt per 24 h) | 0.25 ± 0.03 (n = 31)a | 0.16 ± 0.01 (n = 46) |
| Serum osm (mosm/kgH2O) | 309 ± 4 (n = 5) | 313 ± 34 (n = 6) |
| Serum Na+ (mM) | 145.8 ± 1.0 (n = 5)a | 149.8 ± 1.1 (n = 6) |
| Plasma/serum K+ (mM) | 6.3 ± 0.2 (n = 10)a | 5.6 ± 0.1 (n = 16) |
| Mean BP (mmHg) | 127 ± 2 (n = 13) | 135 ± 3 (n = 19) |
| Mean HR (beats/min) | 632 ± 18 (n = 13) | 630 ± 13 (n = 19) |
Data are means ± SEM.
aP < 0.05.
bP < 0.01.