Table 2.

Predictors of moderate and severe CKD progression

Parameter	No Decline in Kidney Function (Rate of eGFR Change >0 ml/min per year) (n = 1604)		Mild CKD Progression (eGFR Loss 0 to 1 ml/min per year) (n = 426)	Moderate CKD Progression (eGFR Loss 1 to 4 ml/min per year) (n = 1147)		Severe CKD Progression (eGFR loss >4 ml/min per year) (n = 994)
	OR	95% CI	OR	OR	95% CI	OR	95% CI
Age	0.983a	0.971 to 0.995a	1.000	1.002	0.990 to 1.015	0.999	0.986 to 1.012
Black versus white	1.307	0.893 to 1.912	1.000	1.246	0.839 to 1.851	1.853a	1.257 to 2.733a
Other versus white	0.538	0.280 to 1.036	1.000	0.540	0.269 to 1.084	0.453a	0.213 to 0.964a
Female versus male	1.030	0.662 to 1.602	1.000	1.062	0.668 to 1.688	1.107	0.688 to 1.781
Hypertension	1.054	0.712 to 1.561	1.000	1.307	0.854 to 2.000	1.614a	1.013 to 2.571a
Diabetes	0.921	0.737 to 1.152	1.000	1.193	0.947 to 1.504	1.387a	1.095 to 1.756a
CVD	1.020	0.807 to 1.289	1.000	1.047	0.820 to 1.336	1.392a	1.080 to 1.793a
PAD	1.212	0.819 to 1.794	1.000	1.512a	1.016 to 2.248a	1.550a	1.038 to 2.314a
Hepatitis C	1.361	0.600 to 3.085	1.000	0.754	0.302 to 1.883	1.320	0.558 to 3.124
DMARDs	1.019	0.801 to 1.295	1.000	1.031	0.802 to 1.325	1.068	0.826 to 1.381
NSAIDs	0.982	0.732 to 1.317	1.000	1.010	0.743 to 1.374	0.939	0.685 to 1.285

Fully adjusted model for additional covariates including cerebrovascular disease, CLD, and dementia.

^aStatistically significant.