Figure 6.

Therapeutic intervention for secondary hyperparathyroidism reduces FMC in HD patients. Differences between pre- and postintervention values are shown as Δ. Postintervention samples are collected 1 month after each intervention. (A) PTX (n = 4) or cinacalcet (25 mg/d; n = 8) to treat secondary hyperparathyroidism in patients with HD reduces RR but does not affect supernatant fetuin-A levels. Solid lines, cinacalcet; dotted lines, PTX. (B) Reduced iPTH levels do not correlate with changes in fetuin-A levels in serum from patients who were treated with cinacalcet. (C) Only RR positively correlates with iPTH reduced by cinacalcet. Pearson correlation coefficient (r) is shown in simple linear regression analysis.