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Minocycline improves the neurologic symptoms in a dose-dependent manner. MINO (−) group (○), MINO (45 mg/kg body wt) group (●), MINO (4.5 mg/kg body wt) group (■), and MINO (0.45 mg/kg body wt) group (▴). The values are expressed as the means ± SEM (n = 6). **P < 0.01; *P < 0.05 compared with the MINO (−) group.
