Fig. 5.
Zebrafish CL are diverged from mammalian IgL. Mammalian kappa (κ) and lambda (λ) regions are outlined to emphasize the clear divergence of teleost and elasmobranch sequences from traditional IgL classification schemes. Zebrafish CL classified as isotypes designated by Haire et al. [24]. Accession numbers for sequences from GenBank are as follows: Mouse, Mus musculus, AC140201, BC080787; Rat, Rattus norvegicus, DZ394090, DQ402471; Pig, Sus domesticus, M59321, M59322; Human, Homo sapiens, NG_000002, BC063599; Dog, Canis familiaris, XM_845215, XM_532962; Rabbit, Oryctolagus cuniculus, X00231, M25621; Platypus, Ornithorhynchus anatinus, AF525122, AF491640; Echidna, Tachyglossus aculeatus, AY113112, AF491643; Chicken, Gallus gallus, XM_415219; Duck, Anas platyrhynchos, X82069; Xenopus, Xenopus laevis, BC082892; Skate, Raja erinacea, JI9209, L25566; Sandbar shark, Carcharhinus plumbeus, U35008, U34992; Horn shark, Heterodontus francisci, L25563; Sturgeon, Acipencer baeri, X90557; Fugu, Takifugu rubripes, AB126061; Tetraodon, Tetraodon nigroviridis, BX572609, CR701925, CR720937; Rainbow trout, Oncorhynchus mykiss, X68521, AJ231628; Carp, Cyprinus carpio, AB035729, AB091120; Crucian carp, Carassius auratus, AB201791; Cod, Gadus morhua, AF104899; Catfish, Ictalurus punctatus, AY165790S2, IPU25704. Alignments were carried out in ClustalW and plotted with DrawGram utility of PHYLIP in TreeView.