Figure 3.
UFP is the most proatherogenic PM fraction. Atherosclerotic lesions were quantitatively analyzed in serial aortic root sections and stained with oil red O. Lesional area was scored as square micrometer per section, averaged ≥25 sections per animal. Group averages are indicated by straight horizontal bars. One FA mouse was an obvious outlier in its group and removed from the atherosclerotic lesion analysis. However, its inclusion did not modify the overall significance. FA mice are represented by dotted circles (n=14), FPs by stripped circles (n=16), and UFPs by filled circles (n=15).