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VSV is able to overcome SV40 ST-induced Akt phosphorylation. The cell line HEK-TERST, which constitutively expresses the SV40 ST, and its parental cell line, HEK-TERV, were infected with VSV at an MOI of 10. Cell lysates were harvested for analysis at 1, 3, and 5 h postinfection. The phosphorylation levels of Akt and the total protein levels of Akt, VSV M, β-actin, and SV40 ST were determined.
