FIG. 5.
Viremia and adaptive immune responses of monkeys infected with MVwt.STAT1blind. (A) Viremia. Each dot represents an animal, and the horizontal line indicates the mean. Mean value of previously published data from monkeys infected with MVwt (dotted horizontal line) are also shown. MVwt data are not available for day 3. (B) Neutralizing antibody response. Sera obtained at 0, 14, and 28 days postinoculation were assayed for MV neutralization. Symbols are as described above. The results are presented as reciprocals of the neutralizing (neut) titer. Each dot represents an animal. The detection limit is indicated by a thin dashed line. (C) MV-specific IFN-γ-secreting T cells. The symbols are as described above. At 28 and 90 days postinfection, PBMC were stimulated with live MV. The results are presented as SFC per million PBMC.