TABLE 1.
Sequences and Mamu-B*17 binding efficiencies of wild-type and mutant epitope peptides
| SIV strain | Epitope | Sequencea | IC50 (nM) | Reference |
|---|---|---|---|---|
| Wild type | Vif HW8 | HLEVQGYW | 29 | 35 |
| 3×, 4×, 5× | Vif HW8 H1Y | YLEVQGYW | 434 | 35 |
| Wild type | Env FW9 | FHEAVQAVW | 7 | 35 |
| 3×, 4×, 5× | Env FW9 H2Y | FYEAVQAVW | 1,313 | 35 |
| Wild type | Nef IW9 | IRYPKTFGW | 7.6 | 16 |
| 3×, 4×, 5× | Nef IW9 I1T, T6I | TRYPKIFGW | 339 | 16 |
| Wild type | Nef MW9 | MHPAQTSQW | 3.7 | 35 |
| 4×, 5× | Nef MW9 M1V | VHPAQTSQW | 294 | 35 |
| Wild type | Cryptic RW9 | RHLAFKCLW | 32 | 34 |
| 5× | Cryptic RW9 W9R | RHLAFKCLR | 948 | 34 |
Bold type indicates positions of sequence substitution.