TABLE 2.

Association between gene expression and viral load^a

Geneb	Unadjusted model		Adjusted model
	Effect estimate (SE)	P value	Effect estimate (SE)	P value
MxA	0.2887 (0.1436)	0.0444	0.8539 (0.4195)	0.0418
IFN-α	0.2163 (0.1363)	0.1126	0.2512 (0.6476)	0.6981
IFN-β	0.2216 (0.1345)	0.0995	0.1693 (0.4987)	0.7343
huTRIM5α	0.0368 (0.1308)	0.7785	0.1539 (0.1439)	0.2851
TRIM22	0.2154 (0.1532)	0.1597	−0.9807 (0.4539)	0.0307

^aA GEE model was fitted to viral load, adjusting for repeated measurements for the same individual. Unadjusted models were fitted for each expression level in order to determine the effect on viral load. An adjusted model was fitted, including all expression variables in the model to determine whether they have an effect while adjusting for other expression levels. Viral load and expression level were log transformed to ensure normality. Boldface type indicates significance.

^bVersus GAPDH.