Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
cTfRMAb-TNFR brain uptake parameters
Mean ± S.E. (n = 4 mice). The fusion protein was administered by IV injection, and brain measurements were made 60 min after injection.
| Parameter | Value | Units |
|---|---|---|
| Brain uptake | 2.8 ± 0.5 | %ID/g |
| BBB PS product | 3.6 ± 0.6 | μl/(min · g) |
| Injection dose | 350 ± 5 | μg/kg |
| cTfRMAb-TNFR brain concentration | 250 ± 45 | ng/g |
| TNFR brain concentration | 65 ± 12 | ng/g |
