Fig. 2.
Effects of DCG-IV on glutamatergic sEPSCs and mEPSCs of lamina II neurons in sham and nerve-injured rats. A and B, original traces of sEPSCs during control and application of 3 μM DCG-IV, 200 μM EGLU, and EGLU plus DCG-IV in one sham and one nerve-injured rat. C and D, cumulative probability plots of sEPSCs of the same neurons in A and B showing the distribution of the amplitude and interevent interval during control, application of 3 μM DCG-IV, and washout. E and G, summary data showing that 3 μM DCG-IV inhibited the frequency of sEPSCs and mEPSCs in sham and nerve-injured rats. F and H, summary data comparing the percentage inhibition of the frequency of sEPSCs and mEPSCs by DCG-IV in sham and nerve-injured rats. Data are presented as means ± S.E.M. *, P < 0.05 compared with the baseline control or the value in the control group.
