Fig. 2.

α2 Knockin mice develop weaker conditioned taste aversion for ethanol. a, male mice (n = 5 for saline injection for both genotypes; n = 5–6 for groups with ethanol injection). b, female mice (n = 5 for saline injection for both genotypes; n = 9–10 for groups with ethanol injection). No differences between saline-treated groups of wild-type and mutant mice of corresponding sex were found (two-way ANOVA). Wild-type mice of both sexes developed significantly stronger CTA than knockin mice of both sexes (comparison of ethanol-treated groups of wild-type and mutant mice of corresponding sex) (males: p < 0.001; females: p < 0.001; two-way ANOVA). Values represent mean ± S.E.M.