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. Author manuscript; available in PMC: 2012 Jan 17.
Published in final edited form as: Vaccine. 2010 Nov 21;29(4):754–762. doi: 10.1016/j.vaccine.2010.11.015

Figure 4. Replication of T. gondii luciferase expressing parasites was significantly reduced in HLA-A*0201 mice immunized with peptide pool with adjuvant 7 days after challenge.

Figure 4

These experiments were performed twice. The results were similar in each experiment. (A) HLA-A02 transgenic mice immunized with peptide pool and adjuvant were protected compared with control mice inoculated with PBS when they were challenged with 10,000 Pru(Fluc)-T. gondii luciferase expressing parasites. There were two replicate experiments. The first experiment is shown. (B) HLA-A02 transgenic mice survival curve after challenge with Type II parasites. Two weeks after last immunization, the transgenic mice immunized with peptide pool and adjuvant or injected with PBS were infected with 10,000 Pru(Fluc) parasites. The survival rates of the two groups were recorded. Differences in survival were significant (p<0.05). This figure shows data from mice in both of the replicate experiments combined (N=9 control and 9 immunized mice).