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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Bioorg Med Chem. 2010 Oct 20;19(1):677–683. doi: 10.1016/j.bmc.2010.10.032

Table 1.

Cytotoxic activity of 7–9, 13 and 14, 20 and 21, 25–33, and 36

cell lines ED50 (µg/mL )

compound Daoy Hep2 MCF-7 Hela
7 - - - -
8 - - - -
9 5.9 10.5 3.4 6.9
13 - - - -
14 - - - -
20 5.2 7.0 6.6 9.0
21 4.4 3.0 7.9 8.9
25 a 8.7 11.3
26 16.6
27 - - - -
28 - - - -
29 - - - -
30 13.2 13.3
31 - - - -
32 - - - -
33 - - - -
36 - - - -
mitomycin 0.1 0.1 0.1 0.2
a

ED50 >20 µg/mL.