Table 2.

High-Risk Failure Modes Identified Across Multiple Oral Chemotherapy FMEAs

Error	Medication-Use Stage	Capecitabine/Imatinib/Temozolomide	Investigational Agent	6-Mercaptopurine	No. of FMEAs
Prescription writing error resulting from shortcuts, miscalculations, or illegible handwriting	Prescribing	●	●	●	5
Inadequate education (eg, provider rushed, language barrier, assumption that education had already occurred)	Prescribing	●		●	4
Error when transmitting prescription to pharmacy	Prescribing	●		●	4
Wrong tablets, liquid, dose, or number of tablets dispensed	Dispensing	●	●	●	5
Data entry/keystroke error	Dispensing	●		●	4
Pharmacist failed to thoroughly verify prescription	Dispensing	●	●		4
Patient did not correctly adhere to regimen (eg, took wrong drug, self-modified, forgot dose)	Administration	●	●	●	5
Patient did not report or incompletely reported adverse effects	Monitoring	●	●	●	5
Provider inaccurately modified dose on basis of laboratory or toxicity assessment	Monitoring	●		●	4
Provider inaccurately modified dose when previous dose was verbally modified, and information was not noted in record	Monitoring	●	●		4

NOTE. Solid circles indicate that a high-risk failure mode was associated with the drug.

Abbreviation: FMEA, failure mode and effects analysis.