Table 2.
Factors Influencing Recommendation for Adjuvant Chemotherapy in Univariate Analyses of 175 Patients Who Were Suitable for Chemotherapy
| Factor | Chemotherapy Recommended (n = 92) | Chemotherapy Not Recommended (n = 83) | P |
|---|---|---|---|
| Grade | |||
| 1 | 3 | 42 | < .001 |
| 2 | 34 | 36 | |
| 3 | 55 | 5 | |
| T stage | |||
| 1a (< 0.5 cm) | 2 | 15 | < .001 |
| 1b (0.5-1 cm) | 2 | 21 | |
| 1c (1-2 cm) | 41 | 42 | |
| 2 (2-5 cm) | 43 | 5 | |
| 3 (> 5 cm) | 4 | 0 | |
| Age, years | < .001 | ||
| < 45 | 24 | 4 | |
| > 45 | 68 | 79 | |
| ER status | |||
| Positive | 61 | 83 | < .001 |
| Negative | 31 | 0 | |
| HER2 status | |||
| Positive | 15 | 2 | .002 |
| Negative | 77 | 81 | |
| LVI status | |||
| Positive | 33 | 13 | .03 |
| Negative | 57 | 67 | |
| Nodal status | .06 | ||
| Negative | 82 | 80 | |
| Isolated tumor cells | 10 | 3 | |
| Pre/perimenopausal | 39 | 25 | .09 |
| Postmenopausal | 53 | 58 | |
| Discussed in 2007 | 36 | 45 | .04 |
| Discussed in 2008 | 56 | 38 |
Abbreviations: ER, estrogen receptor; HER2, human epidermal growth factor receptor 2; LVI, lymphovascular invasion.