Table 2.
Association between MUC1 tagSNPs and risk of stomach cancer
| SNP | Controlsa | Casesa | ||
|---|---|---|---|---|
| Genotype | n | n | OR (95% CI) b | |
| rs6427184c | TT | 299 | 191 | Reference |
| CT | 76 | 80 | 1.69 (1.17–2.44)* | |
| CC | 0 | 0 | -- | |
| CT/CC | 76 | 80 | 1.69 (1.17–2.44)* | |
| rs4971052 | GG | 151 | 80 | Reference |
| AG | 178 | 126 | 1.33 (0.93–1.90) | |
| AA | 45 | 66 | 2.76 (1.72–4.42)** | |
| AG/AA | 223 | 192 | 1.62 (1.16–2.26)* | |
| rs4276913 | TT | 152 | 81 | Reference |
| CT | 177 | 125 | 1.32 (0.93–1.89) | |
| CC | 46 | 66 | 2.68 (1.68–4.28)** | |
| CT/CC | 223 | 191 | 1.60 (1.15–2.23)* | |
| rs4971088 | AA | 122 | 70 | Reference |
| AT | 190 | 120 | 1.10 (0.76–1.61) | |
| TT | 60 | 79 | 2.28 (1.45–3.57)** | |
| AT/TT | 250 | 199 | 1.39 (0.98–1.97) | |
| rs4971092 | AA | 304 | 192 | Reference |
| AG | 67 | 74 | 1.80 (1.23–2.63)* | |
| GG | 5 | 5 | 1.61 (0.45–5.71) | |
| AG/GG | 72 | 79 | 1.79 (1.23–2.59)* | |
| rs4072037 | GG | 103 | 56 | Reference |
| AG | 194 | 121 | 1.14 (0.77–1.70) | |
| AA | 79 | 95 | 2.20 (1.41–3.44)** | |
| AG/AA | 273 | 216 | 1.45 (1.00–2.10) | |
Sum of column did not add up to total study subjects because of missing data.
Odds ratio (95% confidence interval), adjusted for age and sex.
The P value of fitness for Hardy–Weinberg proportion in controls is 0.029.
The permutation P value < 0.05.
The permutation P value < 0.01.