Table 4.
Association between MUC5AC tagSNPs and risk of stomach cancer
| SNP | Genotype | Controlsa | Casesa | OR (95% CI) b |
|---|---|---|---|---|
| rs1541314 | GG | 311 | 216 | Reference |
| AG | 65 | 54 | 1.23 (0.82–1.84) | |
| AA | 0 | 3 | -- | |
| AG/AA | 65 | 57 | 1.30 (0.87–1.94) | |
| rs2014486 | AA | 123 | 72 | Reference |
| AG | 175 | 123 | 1.22 (0.84–1.77) | |
| GG | 79 | 77 | 1.66 (1.08–2.55) | |
| AG/GG | 254 | 200 | 1.35 (0.96–1.92) | |
| rs2075859 | CC | 192 | 123 | Reference |
| CT | 148 | 110 | 1.16 (0.83–1.63) | |
| TT | 36 | 37 | 1.57 (0.94–2.62) | |
| CT/TT | 184 | 147 | 1.24 (0.91–1.70) | |
| rs2672785 | AA | 236 | 158 | Reference |
| AG | 130 | 102 | 1.19 (0.85–1.65) | |
| GG | 10 | 13 | 1.94 (0.82–4.58) | |
| AG/GG | 140 | 115 | 1.24 (0.90–1.71) | |
| rs2735733 | CC | 146 | 92 | Reference |
| CT | 165 | 112 | 1.09 (0.76–1.56) | |
| TT | 60 | 65 | 1.73 (1.11–2.68) | |
| CT/TT | 225 | 177 | 1.26 (0.91–1.75) | |
| rs7118568 | CC | 335 | 235 | Reference |
| CG | 39 | 35 | 1.27 (0.78–2.08) | |
| GG | 1 | 2 | 2.60 (0.23–29.25) | |
| CG/GG | 40 | 37 | 1.31 (0.81–2.11) | |
| rs868903 | CC | 106 | 50 | Reference |
| CT | 183 | 147 | 1.74 (1.16–2.60) | |
| TT | 84 | 74 | 1.92 (1.21–3.05) | |
| CT/TT | 267 | 221 | 1.80 (1.22–2.63)* | |
| rs4963049 | AA | 305 | 231 | Reference |
| AG | 67 | 40 | 0.76 (0.50–1.17) | |
| GG | 3 | 1 | 0.43 (0.04–4.21) | |
| AG/GG | 70 | 41 | 0.75 (0.49–1.15) |
a
Sum of column did not add up to total study subjects because of missing data.
b
Odds ratio (95% confidence interval), adjusted for age and sex.
*
The permutation P value < 0.05.