Appendix B.
Association between MUC6 tagSNPs and risk of stomach cancer
| SNP | Genotype | Controlsa | Casesa | OR (95% CI) b |
|---|---|---|---|---|
| rs1128413 | TT | 106 | 71 | Reference |
| CT | 187 | 135 | 1.08 (0.74–1.57) | |
| CC | 82 | 67 | 1.24 (0.80–1.94) | |
| CT/CC | 269 | 202 | 1.13 (0.79–1.61) | |
| rs4077293 | CC | 154 | 120 | Reference |
| CT | 182 | 125 | 0.88 (0.63–1.23) | |
| TT | 39 | 24 | 0.79 (0.45–1.39) | |
| CT/TT | 221 | 149 | 0.87 (0.63–1.19) | |
| rs7483870 | GG | 227 | 173 | Reference |
| AG | 133 | 87 | 0.86 (0.62–1.21) | |
| AA | 14 | 11 | 1.03 (0.45–2.33) | |
| AG/AA | 147 | 98 | 0.88 (0.64–1.21) | |
| rs7943115 | CC | 132 | 93 | Reference |
| CT | 188 | 128 | 0.95 (0.67–1.34) | |
| TT | 54 | 51 | 1.37 (0.86–2.20) | |
| CT/TT | 242 | 179 | 1.04 (0.75–1.45) | |
| rs11602663 c | GG | 246 | 184 | Reference |
| AG | 125 | 79 | 0.83 (0.59–1.17) | |
| AA | 5 | 9 | 2.38 (0.78–7.26) | |
| AG/AA | 130 | 88 | 0.89 (0.64–1.24) | |
| rs11605303 | CC | 329 | 233 | Reference |
| CT | 47 | 39 | 1.19 (0.75–1.89) | |
| TT | 1 | 1 | 1.44 (0.09–23.42) | |
| CT/TT | 48 | 40 | 1.20 (0.76–1.89) | |
| rs10902076 | GG | 151 | 94 | Reference |
| CG | 160 | 133 | 1.36 (0.96–1.93) | |
| CC | 64 | 44 | 1.13 (0.71–1.81) | |
| CG/CC | 224 | 177 | 1.30 (0.94–1.80) | |
| rs2071174 | AA | 166 | 135 | Reference |
| AG | 175 | 119 | 0.84 (0.60–1.16) | |
| GG | 36 | 19 | 0.62 (0.34–1.14) | |
| AG/GG | 211 | 138 | 0.80 (0.58–1.09) | |
| rs11245936 | CC | 322 | 232 | Reference |
| CT | 50 | 40 | 1.12 (0.71–1.76) | |
| TT | 0 | 1 | - | |
| CT/TT | 50 | 41 | 1.15 (0.74–1.80) | |
| rs10794359 | CC | 118 | 84 | Reference |
| CT | 189 | 148 | 1.10 (0.77–1.56) | |
| TT | 70 | 39 | 0.77 (0.48–1.25) | |
| CT/TT | 259 | 187 | 1.01 (0.72–1.42) | |
| rs7112267 | GG | 286 | 201 | Reference |
| AG | 81 | 63 | 1.09 (0.75–1.59) | |
| AA | 6 | 5 | 1.22 (0.36–4.07) | |
| AG/AA | 87 | 68 | 1.10 (0.76–1.59) | |
| rs12574439 | GG | 282 | 207 | Reference |
| CG | 90 | 61 | 0.93 (0.64–1.36) | |
| CC | 4 | 5 | 1.77 (0.46–6.72) | |
| CG/CC | 94 | 66 | 0.97 (0.67–1.39) | |
| rs7119740c | GG | 331 | 238 | Reference |
| CG | 38 | 34 | 1.25 (0.76–2.05) | |
| CC | 4 | 1 | 0.37 (0.04–3.31) | |
| CG/CC | 42 | 35 | 1.17 (0.72–1.89) | |
| rs11601642 | AA | 123 | 81 | Reference |
| AC | 175 | 139 | 1.23 (0.85–1.76) | |
| CC | 77 | 52 | 1.05 (0.66–1.65) | |
| AC/CC | 252 | 191 | 1.17 (0.83–1.65) |
a
Sum of column did not add up to total study subjects because of missing data.
b
Odds ratio (95% confidence interval), adjusted for age and sex.
c
The P value of fitness for Hardy–Weinberg proportion in controls is 0.013, 0.021 for rs11602663 and rs7119740, respectively.