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. 2010 Dec 26;7(1):1–8. doi: 10.7150/ijbs.7.1

Figure 2.

Figure 2

The benefit of the subtraction scheme for subtle BBB opening. T1-MRIs of two adjacent slices (A-F and G-L) of a small stroke pre-contrast (A, G), immediately post contrast (B, H), and ~15 min post contrast (C, I). Maps calculated by subtracting the pre-contrast images from the images acquired ~15 min post contrast (D, J) show both vessels and BBB disruptions as positive signals (red). Maps calculated by subtracting the immediate post-contrast images from those acquired ~15 min later (E, K) show vessels as negative signals (blue) and BBB opening as positive signals (red).