Table 2.
High-Risk Patterns in PEROX Model for 1-Year Death or MI
| Pattern | n | Rate, % | HR (95% CI) | |
|---|---|---|---|---|
| Death, high risk | ||||
| 1 | Hgb content distribution width >3.93 and RBC hgb concentration mean <35.07 | 815 | 13* | 4.94 (3.88–6.30) |
| 2 | Hypochromic RBC count >189 and Hgb content distribution width >3.93 | 658 | 13* | 4.47 (3.48–5.73) |
| 3 | Mean corpuscular Hgb concentration <34.38 and perox d/D <0.89 | 466 | 14* | 4.46 (3.42–5.81) |
| 4 | Hypochromic RBC count >189 and macrocytic RBC count >192 | 588 | 13* | 4.37 (3.39–5.64) |
| 5 | Mean corpuscular Hgb concentration <33.00 and mononuclear central x channel <14.38 | 422 | 14* | 4.37 (3.33–5.74) |
| 6 | Age >67 and hematocrit <36.45 | 515 | 13* | 4.08 (3.13–5.32) |
| 7 | Mononuclear polymorphonuclear valley <18.50 and peroxidase y sigma >9.48 | 474 | 13* | 3.85 (2.93–5.07) |
| 8 | Mononuclear central x channel <14.38 and peroxidase y mean >19.02 | 494 | 12* | 3.68 (2.80–4.85) |
| 9 | C-reactive protein >13.75 and history of hypertension | 531 | 12* | 3.63 (2.77–4.76) |
| MI, high risk | ||||
| 1 | Mean platelet concentration >27.89 and potassium <3.85 | 332 | 5† | 2.17 (1.33–3.56) |
| 2 | Triglycerides <130 and age >76 | 464 | 5† | 1.94 (1.23–3.04) |
| 3 | RBC distribution width >13.83 and lymphocyte count >1.75 | 371 | 5† | 1.93 (1.18–3.17) |
| 4 | Hypochromic RBC count >56 and diabetes mellitus | 1212 | 4† | 1.91 (1.37–2.68) |
| 5 | Body mass index <24.7 and neutrophil count <3.58 | 446 | 4† | 1.91 (1.20–3.03) |
| 6 | Systolic blood pressure >150 and history of hypertension | 1163 | 4† | 1.89 (1.35–2.66) |
| 7 | Polymorphonuclear cluster x axis mode >29.87 and RBC distribution width >13.22 | 729 | 4† | 1.80 (1.22–2.67) |
| 8 | Hgb distribution width >2.69 and peroxidase y sigma >8.59 | 842 | 4† | 1.79 (1.23–2.61) |
| 9 | Platelet concentration distribution width <5.39 and RBC hgb concentration mean <34.69 | 870 | 4† | 1.79 (1.23–2.60) |
| 10 | Mean corpuscular hemoglobin >32.60 and male | 500 | 4† | 1.78 (1.13–2.81) |
| 11 | Lymphocyte count <0.96 and potassium >4.4 | 387 | 4† | 1.73 (1.04–2.87) |
| 12 | Platelet concentration distribution width >6.04 and monocyte count >0.46 | 119 | 4† | 1.7 (0.71–4.06) |
| 13 | Neutrophil cluster mean y <71.19 and current smoker | 447 | 4† | 1.69 (1.04–2.74) |
| 14 | Mean platelet concentration >23.19 and basophil count >0.12 | 178 | 3† | 1.36 (0.61–3.03) |
Hgb indicated hemoglobin; RBC, red blood cell. Shown above are high-risk patterns present in the population, with n representing the number of patients in the derivation cohort in each pattern. The event rate within each pattern and HR (95% CI) are shown for each pattern based on univariate Cox models for ranking purposes. Units for each variable are shown in Table 1.
*
Death rate.
†
MI rate.