Table 3.
Low-Risk Patterns in PEROX Model for 1-Year Death or MI
| Pattern | n | Rate, % | HR (95% CI) | |
|---|---|---|---|---|
| Death, low risk | ||||
| 1 | RBC hgb concentration mean >35.07 and hematocrit >42.25 | 1443 | 1* | 0.18 (0.10–0.31) |
| 2 | Macrocytic RBC count <192 and age <67 | 2283 | 1* | 0.22 (0.15–0.32) |
| 3 | RBC Hgb concentration mean >35.07 and RBC count >4.42 | 1494 | 1* | 0.24 (0.15–0.38) |
| 4 | Mean platelet concentration >27.52 and age <67 | 1651 | 1* | 0.24 (0.16–0.38) |
| 5 | Peroxidase y sigma <8.10 and age <67 | 1982 | 1* | 0.26 (0.17–0.38) |
| 6 | C-reactive protein <4.0 and hematocrit >42.25 | 1688 | 1* | 0.26 (0.17–0.40) |
| 7 | Hematocrit >42.25 and perox d/D >0.89 | 1972 | 1* | 0.27 (0.18–0.40) |
| 8 | Mononuclear polymorphonuclear valley >18.50 and age <67 | 1750 | 1* | 0.27 (0.18–0.41) |
| 9 | RBC Hgb concentration mean >35.07 and white blood cell count <5.86 | 1436 | 1* | 0.30 (0.19–0.46) |
| 10 | Neutrophil count <3.96 and age <67 | 1697 | 2* | 0.34 (0.23–0.49) |
| MI, low risk | ||||
| 1 | No history of cardiovascular disease and RBC distribution width <13.22 | 919 | 1† | 0.31 (0.15–0.63) |
| 2 | Lymphocyte/large unstained cell threshold <44.50 and blasts <0.51% | 946 | 1† | 0.34 (0.17–0.66) |
| 3 | Systolic blood pressure <134 and basophil count <0.03 | 743 | 1† | 0.34 (0.16–0.73) |
| 4 | Platelet clumps >41 and fasting blood glucose <92.5 | 782 | 1† | 0.37 (0.18–0.76) |
| 5 | Hemoglobin distribution width <2.69 and hypochromic RBC count <14 | 891 | 1† | 0.41 (0.22–0.77) |
| 6 | Hypochromic RBC count <14 and Neutrophil count <5.83 | 1159 | 1† | 0.43 (0.25–0.74) |
| 7 | Mononuclear central x channel <12.70 and neutrophil y cluster mean >69.30 | 841 | 1† | 0.44 (0.23–0.82) |
| 8 | Mononuclear polymorphonuclear valley >14.50 and creatinine <0.75 | 910 | 1† | 0.44 (0.24–0.81) |
| 9 | No history of cardiovascular disease and systolic blood pressure <134 | 756 | 1† | 0.44 (0.23–0.86) |
| 10 | No. of peroxidase-saturated cells <0.01 and neutrophil count <4.69 | 781 | 1† | 0.47 (0.25–0.90) |
| 11 | HDL cholesterol >59 and mean platelet concentration <28.56 | 830 | 1† | 0.49 (0.27–0.90) |
| 12 | Mononuclear central x channel <12.70 and C-reactive protein <5.31 | 896 | 1† | 0.49 (0.27–0.88) |
| 13 | Mononuclear central x channel <12.70 and basophil count <0.07 | 961 | 1† | 0.54 (0.31–0.93) |
| 14 | No history of cardiovascular disease and neutrophil cluster mean x <66.07 | 1261 | 2† | 0.57 (0.36–0.92) |
RBC indicates red blood cell; Hgb, hemoglobin. Shown are low-risk patterns present in the population, with n representing the number of patients in derivation cohort in each pattern. The event rate within each pattern and HR (95% CI) are shown for each pattern based on univariate Cox models for ranking purposes. Units for each variable are shown in Table 1.
*
Death rate.
†
MI rate.