Table 6.

AUC Values of Models With/Without PEROX Risk Scores for Adverse Cardiac Events at the 1-Year Follow-Up Stratified According to Primary Versus Secondary Prevention Status

	Primary Prevention (n=1859)	Secondary Prevention (n=5510)
Death events, n	40	256
Without PEROX	69	70
With PEROX	81	80
P	0.009	<0.001
MI events, n	23	169
Without PEROX	58	62
With PEROX	71	68
P	0.072	0.007
Death/MI events, n	63	416
Without PEROX	64	65
With PEROX	78	75
P	<0.001	<0.001

ROC curves and AUCs were calculated for 1-year death, MI, and combined death or MI end points. ROC curves for the models with/without PEROX were constructed, and the corresponding AUC values were compared. One-year predicted probabilities of an adverse cardiac event were estimated from the Cox model. P values shown represent a comparison of AUC values estimated from models with and without PEROX risk score among primary prevention or secondary prevention subjects within the whole cohort (n=7369). Both models were adjusted for traditional risk factors including age, gender, smoking, LDL cholesterol, HDL cholesterol, systolic blood pressure, and history of diabetes mellitus.