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. Author manuscript; available in PMC: 2011 Jan 4.
Published in final edited form as: Dev Dyn. 2009 Oct;238(10):2459–2470. doi: 10.1002/dvdy.22062

Table 2. Expression of the Pitx2c N-terminus on the left side of the embryo randomizes the direction of heart looping.

% Abnormal (Leftward) Heart Looping
Retroviral Construct Injected on Left Injected on Right Uninjected
Pitx2c Δ N-ter 5% (n=1/18)
χ2 = 0.36 (N.S.)		 Not tested 10% (n=11/110)
Pitx2c N-ter 27% (n=27/100)
χ2 = 10.21 (p<0.001)		 3% (n=1/28)
χ2 = 1.16 (N.S.)